Nearly three years after Massachusetts voters overwhelmingly approved marijuana for medicinal use, the state’s first dispensary is poised to open Wednesday in Salem.

But in striking contrast to the hoopla that has surrounded the state’s dispensary selection process, Alternative Therapies Group plans a decidedly low-key debut — with patients accepted by appointment only.

State regulators signed off on the final paperwork Tuesday allowing the dispensary to open.

Access to the dispensary, which is in a converted factory building that houses other businesses, will be restricted to patients with a state-issued marijuana registration card, according to the company. Even then, patients will not see any products on display, but will make their choices via a computer screen, according to Salem’s police chief, Mary Butler. [Read more at the Boston Globe]